DNA methylation is a frequent epigenetic mechanism that participates in transcriptional repression.Variations in DNA methylation with respect to gene expression are constant, and, for unknown reasons, some genes with highly methylated promoters are sometimes overexpressed.In this study we have analyzed the expression and methylation patterns of tho
Highlights Novel enzyme-induced proximity labeling technology in nanoparticles Gloves (nano-EPL).Nano-EPL enables dynamic molecular mapping of the intracellular delivery of nanoparticles in macrophages.Nano-EPL enables the elucidation of a comprehensive phagosome-centered timeline during the vesicular transportation of nanoparticles, revealing dist
Stove Element Clip This article presents a model for Customer Lifetime Value (CLV) tailored to the subscription-based streaming industry, incorporating both contractual dynamics and user activity.Unlike traditional CLV models that overlook contracts, this semi-Markov model captures the time users remain in specific subscription plans and the transi